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Bakar Labs
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The Biotech Founder’s Guide to Finding Affordable Lab Space That Supports Growth

Bakar Bio Labs at the University of California Berkeley and Venture Catalyst at the University of California Davis are two examples that offer these types of opportunities. For instance, UC Berkeley is one of the leading public universities in the country, particularly in STEM fields, explained Gino Segrè, PhD, managing director of Bakar Bio Labs, a life science–focused incubator for startups. “So you’re getting all of that when you lease space at Bakar Labs—access to the campus, shared resources, advanced equipment, paid-for student interns, and perhaps faculty advisors—all set in the backdrop of a very vibrant urban environment.” Read post

Profluent Bio Announces Strategic Collaboration with Ensoma to Develop AI-Designed Base Editors for In Vivo Hematopoietic Stem Cell Therapies

Profluent, a leader in frontier AI for protein design, today announced that it has entered into a strategic collaboration with Ensoma, an in vivo cellular engineering company with a mission to advance the future of medicine through one-time therapies. Under the agreement, the companies will leverage Profluent’s AI-designed deaminases in connection with Ensoma’s gene editing scaffolds and helper-dependent adenovirus (HDAd) delivery systems to design, develop, and evaluate AI-designed base editors for in vivo hematopoietic stem cell (HSC) therapies, which will inform future translational decisions. Read post

Azalea Therapeutics Presents New Preclinical Data Demonstrating Robust In Vivo Generation of TRAC-CAR T Cells Using Enveloped Delivery Vehicles

Azalea’s dual-vector platform combines T cell-targeted EDVs delivering Cas9 RNP complexes with a human T cell-tropic AAV carrying a promoterless CAR template. This approach enables precise genomic insertion at the TRAC locus, bringing CAR expression under the control of the native T cell receptor promoter. In vivo TRAC insertion is designed to improve potency, persistence and safety by achieving regulated, physiologic CAR expression rather than continuous signaling from exogenous promoters. Read post
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Hermes Biosciences Raises Seed Funding to Make Extracellular Vesicles a Practical Tool for Precision Medicine

Hermes Biosciences, a life science tools company developing a benchtop, hands-off system for the isolation of extracellular vesicles (EVs), today announced it raised a Seed financing round to deliver its first commercial instrument in 2026, aimed at clinical researchers across academia, Pharma, and clinical customers who require standardized, scalable workflows. The round was led by Genoa Ventures, with participation from Paladin Capital Group and Vertical Venture Partners. Pre-Seed capital and company formation support were also provided by Genoa’s venture studio, General Inception. Read post
Profluent CEO Ali Madani photographed in the QB3 office.

East Bay AI biotech company raises $106 million from Jeff Bezos and others

Profluent Bio, a three-year-old Emeryville company, was the first to show that large language models can generate functional proteins. It went on to design the first CRISPR genome-editing system from scratch, creating an open-source gene editor known as OpenCRISPR-1. With its new-found cash from Altimeter and Bezos Expeditions, it now hopes to continue applying its genome editors into antibodies, enzymes and immune system-triggering antigens. It already has cut deals with a handful of partners, such as life sciences tools company Revvity Inc. (NYSE: RVTY) — the former PerkinsElmer Inc. — agricultural player Corteva Inc. (NYSE: CTVA) and the Rett Syndrome Research Trust, to make custom proteins. Read post

Profluent Raises $106M to Scale Frontier AI Models for Programmable Biology

Profluent, a leader in frontier AI for protein design, today announced a $106 million financing co-led by Altimeter Capital and Bezos Expeditions, with participation from existing investors including Spark Capital, Insight Partners, and Air Street Capital. This round brings Profluent’s total funding to $150 million and will accelerate its mission to make biology programmable – transforming how therapeutics, diagnostics, agriculture, and biomanufacturing solutions are developed. Read post
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