Profluent is using deep generative models to ‘learn the language of biology’ in order to design new, functional proteins.
The goal of protein design is to create novel or enhanced proteins with specific uses. These could include lasting cures for diseases that are free from patent restrictions or new enzymes that can break down unrecyclable plastics.
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“Don and I got to talking and we decided, let's try to get these assets out of Novartis and found Via Nova. A little over a year ago, we were able to execute on a Series A, to get an initial funding of $20 million, which also enabled the in-licensing of the assets from Novartis. The four that we chose are for influenza, human rhinovirus, BK polyomavirus and adenovirus.”
Two scientists without a team or a lab raised $20 million? You heard right. That funding came from Aditum Bio, an investment firm founded by former Novartis scientists who could appreciate that millions of dollars had already been invested into the R&D for these assets.
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Congratulations to Forell Elsesser, the engineering firm contracted for the seismic retrofit that turned the former Berkeley Art Museum from a structural liability to the Bakar BioEnginuity Hub, a robust building home to the Bakar Labs incubator!
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Interior Design's Best of Year is the design industry's premiere design awards program, honoring the most significant work of the year as well as recognizing designers, architects, and manufacturers from around the globe.
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Venture capital into the food tech sector has been waning recently. However, by making flavors and also using them, Kumar believes Black Sheep Foods’ new funding is the result of setting the company up for a vertical integration approach that puts it in a unique space done only by Impossible Foods thus far. He adds the new round was planned and follows progress on some of the key things the company has set out to do in 2022, including the rate of product adoption and R&D milestones on its flavors.
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CEO Greg Went appreciates that our time on Earth is short. What he cares about is helping patients with medicines that work. He doesn’t have time for the ego that some scientists have tied up in the technologies they’re developing. He admits that, early on, even his company was too into itself. “What Reflexion lacked early on was the mentality of ‘why develop this technology if it’s not better than monoclonal antibodies.’ ‘Same as’: we don’t need that. We need products that are a factor of two to ten times better than the standard of care.”
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Every aspect of our building is innovative!
“What we ended up with was this really cool system of ‘stealth’ looking concrete walls,” Price explains. “They had extreme angles – from 45 degrees to 60 degrees, that were top-cast finished with an EcoSand final finish.”
Being large stretches of concrete, there was also concern about skateboarders, so a custom stainless-steel system of skateboard deterrence was designed to replicate the human genome and installed on the face of the battered walls.
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But while continuing to work in Africa with the Clinton Health Access Initiative, she learned she couldn't get far enough away. People were surprised when they learned that the nearly 6-foot-tall, athletic-looking Digovich — a former basketball player in college — was living with Type 1 diabetes, a diagnosis in Africa that often translates into stunted growth, amputation and high mortality. "Ultimately, I got really angry and the switch flipped. If I was born there, I would be dead. That really hit close to home," she said. "I took stock of my career and threw myself into the diabetes space."
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The Bakar BioEnginuity Hub is a winner for the 2022 Preservation Design Award for Rehabilitation. Award recipients are selected by a jury of top professionals in the fields of architecture, engineering, planning, and history, as well as renowned architecture critics and journalists.
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The three companies win free lab space for a year, with access to our facilities and UC Berkeley ecosystem, and connections to AbbVie experts and industry-scale resources.
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“Getting the science right is hard enough, but at least I was trained to be a scientist,” says CSO and former CEO Wesley Jackson. “The skill that I had to learn the quickest was to keep all the company’s stakeholders aligned. I naively assumed that if the science was great enough, it would be sufficient to launch the business. But, instead, I found that a company can only exist because there is a team of people who have an interest in it existing."
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Valitor Inc. and its platform technology — spun out of the work of University of California professors Kevin Healy and David Schaffer — looks to take on big players in the ophthalmology space, namely Genentech Inc. and its wet age-related macular degeneration drug Lucentis and Regeneron Pharmaceuticals Inc.'s Eylea.
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The company will spend next year testing its multivalent polymer to prep for a clinical trial in 2024. The goal is to create an injectable that can last six months, meaning patients with wet AMD, a chronic eye condition that blurs vision and can sometimes cause blind spots, would only need two injections per year, kind of like going to the dentist, quipped Wesley Jackson, co-founder, president and CSO, in an interview with Endpoints News ahead of the launch.
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Receiving the SBIR award from NIH on the heels of the FDA approving our lead candidate RVB-001 for the Rare Pediatric Designation is further proof of our vision to treat inflammatory skin diseases with topical cellular therapies,” said ResVita CEO Amin Zargar.
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“We can’t make more land, so we need to be more efficient with it. One way to do this is to make plants fundamentally better at photosynthesis. If you make photosynthesis better, you solve a lot of problems at the same time. You increase food security, you can pull CO2 out of the atmosphere for the long term, and you can spare land for biodiversity.”
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Chris Paul, known by his fans as CP3, became a vegan in 2018 and credits the change in diet with improving his on-court performance. The elite athlete and investor is committed to aligning his business ventures with a social impact mission, including better health outcomes for underserved and low-income communities.
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Congratulations to Glyphic Biotechnologies! NIH recently reported the company had been awarded a $409 SBIR grant for their project "Single-molecule protein sequencing by iterative isolation and identification of N-terminal amino acids." The company is developing and commercializing technology to sequence proteins — instead of DNA. They're hiring!
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Co-founded last year with fellow Berkeley alum Daniel Estandian, VC-funded Glyphic Biotechnologies’ single-molecule protein sequencer may upend the way that pharmaceuticals are developed. By modifying the standard process for sequencing proteins — including the use of a novel molecule that improves identification — their results are not only more accurate but also significantly faster than the predominant methods being used today.
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